This is the blog for GW students taking Human Evolutionary Genetics. This site is for posting interesting tidbits on: the patterns and processes of human genetic variation;human origins and migration; molecular adaptations to environment, lifestyle and disease; ancient and forensic DNA analyses; and genealogical reconstructions.

GWHEG figure

GWHEG figure

Friday, April 27, 2018

Non Potluck: Adaption to unfavorable conditions



The Maipo River in Chile is considered to be highly polluted. Within the river lives a species of fish known as Basilichthys microlepidotus in which different populations occupy either polluted or non polluted areas of the river. A study was done to investigate if environmental pollution is related to phenotypic or genotypic selection. To find this, a transcriptomics approach based on RNA seq was used to determine differentially expressed genes from the populations living in polluted areas versus non polluted areas. The results showed that in one population from a polluted site there was an unregulated gene found related to suppression and progression of tumors, while in another population from a polluted site there was an unregulated gene related to function of apoptotic was over expressed. These results showed a plastic response in expression due to anthropogenic pollution.


The article from Nature can be found here

Sam

(Nature review 1/3)

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