This is the blog for GW students taking Human Evolutionary Genetics. This site is for posting interesting tidbits on: the patterns and processes of human genetic variation;human origins and migration; molecular adaptations to environment, lifestyle and disease; ancient and forensic DNA analyses; and genealogical reconstructions.

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Monday, February 3, 2020

U.S. Attitudes on Human Genome Editing



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We have come along way from sequencing the human genome; it is now possible now to edit genes for therapeutic or enhancement purposes. This study investigated how the United States public regards gene enhancement. 1,600 US adults were surveyed in December 2016 and January 2017. Two thirds reported somatic and germline therapy to be acceptable in their opinion, but there were lower rates of acceptance for germline or somatic enhancement therapy.

To explore what drives opinion on gene editing, the authors investigated personal variables such as religious beliefs and knowledge on the subject. Those reporting a high level of religious guidance were less likely to support both treatment and enhancement gene editing compared to those who reported a low level of religious guidance. Those able to correctly answer more of the provided factual questions about gene editing were more likely to support for genome editing. Individuals in the low knowledge group were more likely to report that they neither support or opposed gene editing.  Both the highly religious and highly informed demonstrated the most support for public engagement and consulting the public. However, the highly religious expressed more doubts about scientists' abilities to control gene editing. The authors conclude this highlights the need for more public engagement. As technology advances, scientists have a responsibility to keep in mind public opinion, as they will be the primary consumers of this technology.

https://science.sciencemag.org/content/sci/357/6351/553.full.pdf

Rachel Nelson (Potluck, Human Genome 2/4)

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