This is the blog for GW students taking Human Evolutionary Genetics. This site is for posting interesting tidbits on: the patterns and processes of human genetic variation;human origins and migration; molecular adaptations to environment, lifestyle and disease; ancient and forensic DNA analyses; and genealogical reconstructions.

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GWHEG figure

Monday, March 26, 2018

Regulatory pathway analysis of coat color genes in Mongolian horses





Unlike previous work that focused on gene polymorphism, the current research evaluates the impact of gene expression on horses coat coloration. Skin samples were collected from horses with white and black coat colors and the genes were identified through the use of RNA sequencing. In this study Li and his colleagues were able to provide a collection of genes that are differentially expressed in horse skins of different colors. Their findings indicate that the genes such as DCT, HPD and TAT  are involved in tyrosine metabolism which is responsible for melanin production. The authors indicate that the deregulation of these genes is associated to formation of coat coloration and skin health issues

Here is the link of the original paper:

https://hereditasjournal.biomedcentral.com/articles/10.1186/s41065-017-0048-y

Axelle



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