The CRISPR (Clustered Regularly Interspaced Short
Palindromic Repeats)-Cas9 (CRISPR-associated protein 9) system has become a
regular component of genomic engineering studies. However, public support and
understanding of these studies remains uncertain. Recently, Brokowski and Adli
outlined the various ethical issues related to CRISPR and proposed a framework
for regulating future studies. Their review particularly highlighted the uncertainty
associated with human germline genetic modifications and their risks. Another concern
is the likely possibility of class inequality affected access to CRISPR
technology and subsequent price gouging. While human clinical CRISPR trials
will be necessary at some point, these cannot be established without a firm ethical
framework. Overall, they recommend the establishment of an organization, such
as the Association for Responsible Research and Innovation in Genome Editing
(ARRIGE), to help address the ethical considerations of human genome editing.
Joshua Porter - Potluck 03/10/2020
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