In vivo CRISPR Editing

An paper in Nature focused on the the topic of how scientists are testing in vivo CRISPR editing in mice.  In the paper the scientists wanted to test how editing genes and targeting certain genes can help stop certain mutations from forming. There has been no way to test the in vivo editing until now, in which the scientists used two types of mice to perform tests. The scientists are testing the in vivo editing on the mice livers to see if there could be any mutations that could be stopped or slowed down. As well as there was carefully designed guide RNA that were used on the livers, both of the strategies are showing some sort of positive change in the mice's gene and can help start the research for more gene editing.